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Diffine is an AI consulting company for the life sciences. We build AI systems for biotech and pharmaceutical clients on two fronts. In imaging and spatial biology: multimodal AI that integrates spatial multi-omics and other data types for biomarker discovery and biological endpoint prediction with explainable readouts; computer vision for digital pathology, fluorescence microscopy, cell painting, and high content screening. In drug discovery: agentic AI systems that work alongside medicinal chemistry teams, models that learn from scientific literature and patents, generative models for molecular design, molecular property and ADMET prediction, and multi-parameter optimization (MPO) that turns a target product profile into transparent, tunable compound prioritization. We deliver end to end: problem framing, data strategy, model development, validation, and deployment in your environment, cloud or on-premises, including integration with discovery informatics platforms.

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9 people are employed at Diffine.

Diffine is based in San Diego, California.

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