.406 Ventures is a Boston-based venture capital firm with over $1.3B under management and two decades of experience leading or co-leading early-stage investments in pioneering healthcare, data + AI, and cybersecurity companies founded by visionary entrepreneurs. Notable lead investments include AbleTo (acquired by Optum), Carbon Black (acquired by VMWare), CloudHealth (acquired by VMware), Corvus (acquired by Travelers), Health Dialog (acquired by BUPA), Iora Health (acquired by One Medical/Amazon), Laudio (acquired by Ascend Learning), MineralTree (acquired by Global Payments), Reltio (acquired by SAP). and Veracode (acquired by CA Technologies).
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The .406 Ventures annual revenue was $9.8 million in 2026.
Joe Santabarbara is the CFO of .406 Ventures.
44 people are employed at .406 Ventures.
.406 Ventures is based in Boston, Massachusetts.
The NAICS codes for .406 Ventures are [52, 5239, 523].
The SIC codes for .406 Ventures are [67, 679].