Imagine a world where genetic diseases are treated with orally-available small molecule drugs. That's the future Sharp Edge Labs is building. Sharp Edge is a preclinical-stage life sciences company developing drugs for genetic diseases. Our monogenic disease focus de-risks the clinical path. Each pipeline program has a genetically identifiable subset of patients and an early Phase IB pharmacodynamic readout. We combine three core techologies to create a scalable platform for discovery and development. CoreX(tm) is s suite of assay technologies that enable the creation of realistic cellular models of genetic diseases. AlloChem(tm) is a proprietary compound library computationally biased to contain molecules that can bind proteins allosterically, stabilizing them, and restoring their function. Disco/Mine(tm) is a suite of computational and machine learning tools that enhances our experimental approach rather than replacing it. These combine to create a scalable platform with over 10 programs at various stages of development. The company has programs in Frontotemporal Dementia, and genetic subsets of Alzheimer’s and Parkinson’s, as well as lysosomal storage disorders and other loss-of-function diseases. The team and its advisors includes ex and current Genzyme/Sanofi, Synageva, Pfizer and Shire executives.
View Top Employees from Sharp Edge LabsWebsite | http://www.sharptx.com |
Revenue | $1 million |
Funding | $2.8 million |
Employees | 11 (11 on RocketReach) |
Founded | 2010 |
Address | 2403 Sidney Street Suite 264, Pittsburgh, Pennsylvania 15221, US |
Phone | (412) 475-9733 |
Technologies |
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Industry | Biotechnology Research, Business Services General, Biotechnology, Cellular Assays, Business Services, Science and Engineering, Molecular Biosensors, Life Science, High-Throughput Screening, Medical Device, High-Content Screening, Health Care |
Web Rank | 28 Million |
Keywords | Biotech Companies In Pittsburgh Usa |
Competitors | Ember Therapeutics, REGENXBIO Inc., Sangamo Therapeutics, Inc., Spark Therapeutics, Inc., bluebird bio |
SIC | SIC Code 873 Companies, SIC Code 87 Companies |
NAICS | NAICS Code 541714 Companies, NAICS Code 5417 Companies, NAICS Code 541 Companies, NAICS Code 54 Companies, NAICS Code 54171 Companies |
Looking for a particular Sharp Edge Labs employee's phone or email?
The Sharp Edge Labs annual revenue was $1 million in 2024.
Marcel Bruchez is the Chief Scientific Officer of Sharp Edge Labs.
11 people are employed at Sharp Edge Labs.
Sharp Edge Labs is based in Pittsburgh, Pennsylvania.
The NAICS codes for Sharp Edge Labs are [541714, 5417, 541, 54, 54171].
The SIC codes for Sharp Edge Labs are [873, 87].