PentaBind Information

Biology is extraordinarily powerful, but many of the molecular tools we rely on today were not designed for the environments, performance requirements or applications we now expect of them. Advances in AI, molecular engineering and experimental biology are changing what is possible. PentaBind brings these disciplines together to engineer molecular recognition for the demands of real-world products. We have spent years building the data and technology to go further. At the heart of PentaBind is the largest dataset of its kind, mapping aptamer sequence to the functional characteristics that determine how a molecule actually performs. Generated through a tightly integrated cycle of computational design and experimental measurement, it gives us something fundamentally different to engineer against: not a single binding event, but a complete molecular performance profile. This is how we are taking aptamers from a research tool to a new standard of biorecognition, starting with SenseReady™ aptamers for wearables, sensing and continuous monitoring. PentaBind is backed and supported by Hoxton Ventures, TwinPath, Entrepreneurs First, NVIDIA Inception, the UK National Nuclear Laboratory and Medicines Discovery Catapult.