Jacob's Cure Information

Jacob’s Cure is a non-profit foundation dedicated to raising the funds necessary to curing Canavan disease, a fatal genetic neurological disorder that affects children at birth. Since it’s inception in September 2000, Jacob’s Cure allocates monies raised to research in gene-therapy, stem cell transplantation, pharmacological approaches and basic science in understanding the disease. Their efforts to date have resulted in successful gene-therapy trials and pharmaceutical interventions that have, in most cases, stopped the progression of this quickly deteriorating disorder in children afflicted with Canavan disease worldwide. In addition, Jacob’s Cure is responsible for creating/funding the Canavan Research lab at UMDNJ/SOM at the direction of Dr. Paola Leone. The efforts at the CR lab focus solely on research and intervention that will save the children dying of Canavan today.