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Wave Neuroscience
Wave Neuroscience is a Newport Beach, California-based neurotechnology company founded in 2019 on a simple premise: mental health is brain health, and biomarker-guided neuromodulation can pioneer a new era in brain health treatment. Wave developed MeRT® (Magnetic e-Resonance Therapy), the first FDA-cleared personalized, EEG-guided neuromodulation system for PTSD. Unlike standard approaches cleared for other mental health conditions that apply the same protocol to every patient, MeRT begins with a quantitative EEG to map each patient’s unique brain activity, then delivers precisely derived transcranial magnetic stimulation (TMS) tailored to their individual neurophysiology. Wave's pivotal clinical trial demonstrated a 52% average reduction in PTSD symptoms — a superior outcome compared to antidepressants, trauma-focused talk therapy, and other FDA-cleared neuromodulation protocols. At the end of treatment, 68% of active participants classified as "in remission" by falling below the clinical threshold for PTSD.(1) Wave's mission is to move mental healthcare from subjective symptom management to measurable, personalized, effective intervention. (1) Pivotal Trial: Multi-site, double-blind, sham-controlled randomized trial (n=158). Primary endpoint: change in PTSD Checklist for DSM-5 (PCL-5) scores. All results favor active MeRT treatment group. Source: U.S. Food and Drug Administration. 510(k) Summary: MeRT® System (K260402). June 3, 2026.
Newport Beach, California, US
Private
https://waveneuro.com
52 Employees
Thought Tech
Thought Technology is the world's leading biofeedback and psychophysiological instrument manufacturer. Our instrumentation not only monitors and records a wide variety of physiological and mechanical signals, but also analyzes and feeds back information in real time, through a variety of auditory and visual means. Our equipment is used as an essential part of many therapeutic treatments and clinical assessment protocols to treat stress related disorders as well as provide treatment for incontinence and muscle rehabilitation, including sEMG-triggered stimulation. On the non-medical side, Thought Technology's Science Division provides equipment and software to be used in ergonomics, sports and educational applications – wherever accurate and sensitive psychophysiological monitoring and biofeedback are needed. Typical signals include surface electromyography (sEMG), electroencephalography (EEG), electrocardiology (EKG), skin conductance, temperature, blood volume pulse, respiration, inclination, pressure and bend.
Montreal, CA
Private
$34.3M Revenue
http://www.thoughttechnology.com
46 Employees
EMOTIV
EMOTIV is a bioinformatics company advancing understanding of the human brain using electroencephalography (EEG). Our mission is to empower individuals to understand their own brain and accelerate brain research globally. Applications for the EMOTIV technology and interface span an incredible variety of industries - from gaming to interactive television, everyday computer interactions, hands-free control system, smart adaptive environments, art, accessibility design, market research, psychology, medicine, robotics, automotive, transport safety, defense and security. EMOTIV is a recognized pioneer and market leader in this field. Our products have won numerous international awards including the Red Dot Award, AutoVision Innovations Award, Australian International Design Awards, Australian Engineering Excellence Awards and Edison Awards. Our community of developers and researchers span over 120 countries.
San Francisco, California, US
Private
$21M Revenue
https://www.emotiv.com
125 Employees

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