SyntheX Information

SyntheX is a biotech company advancing precision drug discovery through synthetic biology. Our proprietary ToRFLEx platform uses genetically engineered circuits and intracellular drug selection to identify novel compounds with unique mechanisms of action. This approach overcomes the limitations of traditional in-vitro and in-silico methods, enabling the discovery of compounds that engage previously uncharacterized binding sites on protein targets. We specialize in targeting protein-protein interactions and developing molecular glues for targeted protein degradation. Our technology has powered our internal oncology pipeline and serves as the foundation for external collaborations, advancing the next generation of safer and more durable therapeutics.