Spirochrome Information

Modern fluorescence microscopy is the method of choice to visualize biomolecules and cellular structures at the nanometer scale. The bottleneck to apply fluorescence microscopy for live-cell and in vivo imaging has become the availability of suitable fluorescent probes. Spirochrome has addressed this bottleneck and established itself as a leader in the design and commercialization of fluorescent probes for live-cell imaging. Our Superior fluorophores and probes have been introduced in a number highly cited papers and have become household names in the imaging community. These probes include SiR-actin, SiR-tubulin, SiR-DNA as well as the new popular SPY™ probes. Our probes cover the entire wavelength range, are fluorogenic and also applicable to superresolution microscopy methods.