SIRC-TCM (SAPHRON® TCM Database, Yuxintine S111) Information

SIRC-TCM is aiming at TCM modernization and innovative drug discovery by integrating modern life science, chemistry, and information technology with TCM. With a high-level R&D team led by PhDs and masters, SIRC-TCM has not only set up a full-function new drug R&D system, covering the fields of TCM informatics, phytochemistry, analytical test, organic synthesis, pharmacology & toxicology, TCM genomics, drug design and kilogram-level workshop, but also successfully established a public service platform of TCM R&D informatics, a research platform of TCM genomics for drug-screening and a synthetic platform for development of saponin drug. SAPHRON™ TCM Database has been developed with more than fourteen-year endeavors by SIRC-TCM and it provides the best in-silicon solution for early stage drug discovery and product development from medicinal herbs. The database contains comprehensive information including 1,400 diseases, 180,000 TCM prescriptions, 9,000 herbs, 50,000 active compound structures and more than 120,000 items of related biological activities. Those enriched andevidence-based TCM information are the foundation for TCM originated product development. High quality TCM information provided by us through a proprietary reliability evaluation system and informatic analysis is the core value of SAPHRON™ TCM Database services. With our sophisticated bioinformatic and statistical tools, we can recommend herbs and active compounds for any target indications as well as their potential biological targets (proteins) for mechanistic study. Based on reliable TCM information, our services can significantly facilitate evidence-based product design for TCM originated pharmaceutical, nutraceutical and cosmetic applications. Our services remarkably shorten R&D cycle with reduced risk of failure.