Osmetech plc Information

Osmetech plc is an AIM-listed public company on the London Stock Exchange. The Company is a fast developing, international diagnostics business with operations in Boston and Pasadena in the US, serving the high growth molecular diagnostic market targeting hospitals and reference laboratories. Osmetech has a strong portfolio of over 200 issued and pending patents and has launched its first generation eSensor 4800 platform, an electrochemistry-based array system, together with an FDA cleared in vitro diagnostic test for Cystic Fibrosis carrier detection. Osmetech's second generation platform, the eSensor XT-8 received FDA 510(k) clearance in July 2008 together with our eSensor Warfarin Sensitivity Test. These products are now being marketed in the U.S. together with a 2C9 Genotyping Test for drug metabolism and a Cystic Fibrosis carrier detection test which are both available for research use purposes only. In April 2009, Osmetech signed a five-year distribution agreement with Fisher HealthCare, a part of Thermo Fisher Scientific, whereby Fisher HealthCare will distribute Osmetech's eSensor XT-8 instrument platform and molecular diagnostic tests and consumables in the U.S. The eSensor XT-8 System is designed to support a broad menu of tests and Osmetech has scheduled for commercial launch a number of further tests including: extended warfarin panel with the proprietary 4F2 marker, venous thrombosis (Factor II, Factor V Leiden and MTHFR) and the RESPLEX II respiratory pathogen assay in-licensed from Qiagen. The System provides accurate results while minimizing technician involvement and its features compare favorably to those of other molecular detection systems. Its ease of use, readily interpretable results, speed and low maintenance are particularly suited to the needs of the decentralizing market.