Fee-for-service hit discovery is backwards. OpenBench offers a simple solution. We bear the cost of virtual screening, synthesis, and experimental confirmation, so that the first dollar our collaborators spend is on potent, developable hit series. This success-driven paradigm fosters rigor, accountability, and operational efficiency. We construct hit criteria jointly with partners to ensure outcomes motivate further hit-to-lead pursuit. Once a deal is in place, our partners receive compounds in their labs in 2 months with validation soon to follow. OpenBench’s technology uniquely enables this success-driven paradigm. We manage scientific risk by picking hits from massive virtual libraries >100x more efficiently than conventional methods. Screening and judiciously filtering billion-compound libraries ensures novelty and developability of hits—traits conventional solutions cannot promise. To sign up for the OpenBench waitlist, please visit https://opnbnch.com
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