ONK Therapeutics, is an innovative cell therapy company dedicated to developing a next generation of off-the-shelf, dual-targeted NK cell therapy platform targeting hematological malignancies and solid tumors. The Company was founded in 2015, by Prof. O’Dwyer MD, of NUI Galway, an expert in translational multiple myeloma research, the tumour microenvironment, and exploitation of NK cells as cellular immunotherapy. Its core proprietary platform is based on a dual-targeted NK cell expressing both a chimeric antigen receptor (CAR) targeting a known tumour antigen and a TNF related apoptosis inducing ligand variant (TRAILv) targeting the death receptor pathway (i.e. DR4 or DR5). This promising new approach has the potential to enhance efficacy by addressing both intrinsic (e.g. CAR engagement of a tumor specific antigen) and extrinsic (e.g. signalling through the death receptor pathway) apoptotic pathways, and to reduce the susceptibility to possible target antigen escape through the engagement of tumor antigen independent TRAILv.
View Top Employees from ONK TherapeuticsWebsite | http://www.onktherapeutics.com |
Employees | 33 (32 on RocketReach) |
Founded | 2015 |
Phone | +353 86 023 9842 |
Technologies |
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Industry | Biotechnology Research, Business Services General, Drug Discovery, Business Services, Biotechnology |
SIC | SIC Code 283 Companies, SIC Code 873 Companies, SIC Code 28 Companies, SIC Code 87 Companies, SIC Code 80 Companies |
NAICS | NAICS Code 541 Companies, NAICS Code 54 Companies, NAICS Code 33 Companies, NAICS Code 3254 Companies, NAICS Code 325 Companies, NAICS Code 32 Companies |
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Chris Nowers is the CEO of ONK Therapeutics.
32 people are employed at ONK Therapeutics.
ONK Therapeutics is based in Galway, County Galway.
The NAICS codes for ONK Therapeutics are [541, 54, 33, 3254, 325, 32].
The SIC codes for ONK Therapeutics are [283, 873, 28, 87, 80].