OncoKB™ is a comprehensive precision oncology knowledge base developed at Memorial Sloan Kettering Cancer Center that annotates the oncogenic effects and clinical actionability of somatic alterations in cancer. OncoKB™ assigns evidence-based levels of clinical actionability to individual mutational events in a tumor type-specific context. As of 2024, OncoKB™ contains annotations for >7500 alterations in >850 cancer-associated genes. In October 2021, OncoKB™ became partially FDA recognized as a public human genetic variant database to support clinical validity for genetic and genomic-based in vitro diagnostics. As of 2024, OncoKB™ has published two articles that outline the precision oncology cancer therapy landscape and detail how OncoKB™ integrates within this landscape: • Suehnholz, et al. Quantifying the Expanding Landscape of Clinical Actionability for Patients with Cancer. Cancer Discovery, 2023. • Chakravarty, et al. OncoKB: A Precision Oncology Knowledge Base. JCO Precision Oncology, 2017. OncoKB™ offers licenses for academic, commercial and hospital use, with which users can programmatically access the web API. Please visit our website for inquiries regarding licenses.
| Website | https://www.oncokb.org/ |
| Employees | 6 (1 on RocketReach) |
| Industry | Biotechnology Research |
| Keywords | Precision Oncology, Cancer Genomics, Molecular Oncology, Oncology Data, Clinical Oncology, Personalized Medicine, Cancer Informatics, Cancer Research, Cancer Treatment, Cancer Genetics, Cancer Biomarkers, Drug Discovery, Cancer Therapies, Clinical Trials |
| Competitors | Tempus Labs, Inc., Guardant Health, Myriad Genetics, Foundation Medicine, Caris Life Sciences, Invitae, Freenome, Biocept, Inc., Strata Oncology, Talis Biomedical Corporation +41 more (view full list) |
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1 people are employed at OncoKB.
OncoKB is based in New York, New York.
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Moriah Nissan
Scientific Relations Manager at OncoKB
New York, NY, US32
