MOL3D RESEARCH , LLC Information

Mol3D Research provides consultancy and research services in computational chemistry, molecular modeling and computer-aided drug design (CADD) for biotechnology and pharmaceutical companies, academic institutions, and non-profit research organizations involved in new drug discovery. We have extensive experience of working with multi-disciplinary teams including medicinal chemists, biologists, pharmacologists and crystallographers in support of drug discovery R&D projects for oncology, metabolism, CNS, virology and bacteriology. We offer comprehensive CADD services with special emphasis on structure-based drug lead discovery and optimization. Mark Shenderovich, PhD, Principal and CSO of Mol3D Research, has 18 years of experience working as a computational chemist for biopharmaceutical industry, and more than 25 years of overall research experience in molecular modeling and CADD. He made critical contribution to the discovery of clinical and pre-clinical drug candidates for Hsp90, protein tyrosine phosphatase, protease and protein kinase targets.Click here for more details. Company name, Mol3D means "molecules in three dimensions". Professor Victor J. Hruby, the post-doctoral advisor of Mark Shenderovich, used to say that Mark's most important contribution to his group was teaching organic chemists to think in three dimensions. Targets for the majority of drugs are three-dimensional biological macromolecules. Pharmaceutical agents, whether small molecules, peptides, nucleotides, proteins or antibodies, should be designed to interact complimentary with their 3D targets. Even a low-resolution model of ligand-receptor complex can inspire medicinal chemists on directions of lead optimization, while high-resolution structures significantly enhance drug design process. The aim of Mol3D Research is to provide our clients with 3D models of drug-target interactions and to help them with computer-aided drug design in three dimensions. Mol3D Research Logo displays an outstanding example of three-dimensional assembly of ...