Metacrine is a clinical-stage biopharmaceutical company pioneering differentiated therapies for patients with liver and gastrointestinal (GI) diseases. Our most advanced programs target the farnesoid X receptor (FXR), which is central to modulating liver and GI diseases. FXR agonism has been investigated in large-scale clinical trials and has shown clinically relevant improvements in non-alcoholic steatohepatitis (NASH), a liver disease that affects 17 million people in the U.S. and is characterized by excess liver fat, inflammation and fibrosis. We believe that potency and continuous target engagement are key to optimizing therapeutic benefit with an FXR targeted therapy. Leveraging our extensive chemistry and biology expertise, we have built a proprietary library of over 2,500 FXR compounds, and have selected two oral FXR candidates from a unique chemical scaffold, MET409 and MET642. With our platform, we believe we can develop differentiated FXR agonist therapies for liver and GI diseases.
View Top Employees from Metacrine, Inc.Website | http://www.metacrine.com |
Revenue | $10 million |
Funding | $245.8 million |
Employees | 16 (16 on RocketReach) |
Founded | 2014 |
Address | 3985 Sorrento Valley Blvd Suite C, San Diego, California 92121, US |
Phone | (858) 369-7800 |
Fax | (858) 369-7825 |
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Industry | Pharmaceuticals, Biotechnology Research, Drug Manufacturing & Research, Biotechnology, Science and Engineering, Drug Discovery, Healthcare, Health Care, Medical |
Web Rank | 7 Million |
Keywords | Metacrine, Metacrine Ipo, Metacrine Inc, Metacrine Careers, San Diego Metabolic Disease Pharm |
Competitors | Equillium, Inc., Harpoon Therapeutics, Inozyme Pharma, TYME Technologies Inc., Visterra Inc. |
SIC | SIC Code 283 Companies, SIC Code 28 Companies |
NAICS | NAICS Code 32 Companies, NAICS Code 3254 Companies, NAICS Code 325 Companies, NAICS Code 32541 Companies |
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The Metacrine, Inc. annual revenue was $10 million in 2024.
Brian Byrnes is the Vice President of Clinical Operations of Metacrine, Inc..
16 people are employed at Metacrine, Inc..
Metacrine, Inc. is based in San Diego, California.
The NAICS codes for Metacrine, Inc. are [32, 3254, 325, 32541].
The SIC codes for Metacrine, Inc. are [283, 28].