Loop Genomics Information

Loop Genomics is the only hardware-free synthetic long read sequencing approach that transforms any short read sequencer into a single molecule long read sequencer. The company has developed proprietary sample prep and software that tag DNA/RNA molecules with DNA barcodes and copies and pastes those barcodes intra-molecularly throughout long molecules. Once barcodes are distributed intra-molecularly, libraries are converted into a standard short read library and sequenced on any short read sequencer. After sequencing, reads with the same barcodes are grouped together and assembled back into the longer molecules that were tagged by those barcode using Loop's software. Loop sequencing is used to assemble genomes, transcriptomes or targeted amplicons from long reads, providing highly accurate, single molecule long read data for any application and leveraging your existing short read infrastructure.