At LAVA, we are focused on applying our expertise in gamma-delta T-cell engagers (TCEs) to transform cancer therapy. We refer to our compounds as gamma-delta bispecific T-cell engagers, or gamma-delta bsTCEs. Our platform generates therapeutics that specifically activate a unique and relatively abundant effector gamma-delta T-cell subset called Vγ9Vδ2 (Vgamma9-Vdelta2) T-cells that have the ability to trigger activity of immune cells of both the innate and adaptive immune system. Our gamma-delta bsTCEs have demonstrated superior efficacy and safety profiles compared to other bsTCE approaches in preclinical studies and show preferential activity against tumor cells thereby potentially limiting toxicity in healthy tissue. To date, we are the only company developing bispecific gamma-delta T-cell engaging antibodies for the treatment of cancer. We are building a pipeline of gamma-delta bsTCEs that have applications in both solid and hematologic malignancies. Our lead program, LAVA-051, targets the tumor specific antigen CD1d, which can be overexpressed in multiple myeloma, chronic lymphocytic leukemia (CLL), and acute myeloid leukemia (AML), among other tumor types. LAVA-051 will enter a Phase I/IIa study in 1Q21.
View Top Employees from LAVA Therapeutics N.V.Website | http://www.lavatherapeutics.com/ |
Ticker | LVTX |
Revenue | $405000 |
Employees | 63 (63 on RocketReach) |
Founded | 2016 |
Address | Yalelaan 60, 5th floor, Utrecht, Utrecht 3584 CM, NL |
Phone | +31 6 30003035 |
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Industry | Pharmaceuticals, Biotechnology Research, Biotechnology, Drug Discovery, Healthcare, Science and Engineering, Life Science, Medical, Health Care |
SIC | SIC Code 283 Companies, SIC Code 28 Companies |
NAICS | NAICS Code 541 Companies, NAICS Code 325 Companies, NAICS Code 32 Companies, NAICS Code 32541 Companies, NAICS Code 54 Companies, NAICS Code 3254 Companies |
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The LAVA Therapeutics N.V. annual revenue was $405000 in 2024.
Fred Powell is the CFO of LAVA Therapeutics N.V..
63 people are employed at LAVA Therapeutics N.V..
LAVA Therapeutics N.V. is based in Utrecht, Utrecht.
The NAICS codes for LAVA Therapeutics N.V. are [541, 325, 32, 32541, 54, 3254].
The SIC codes for LAVA Therapeutics N.V. are [283, 28].