Few can claim 17th century Renaissance Italy as the birthplace of their family start-up. Yet, nearly 400 years and nine generations later, D’Addario & Co. proudly continues to do so. Today, we are globally recognized as the world’s premier instrument accessory manufacturer for strings, drumheads, drumsticks, reeds, mouthpieces and more. Inspired by our past and paving a future path, D’Addario is fueled by an ever-expanding family of musicians, engineers, artists and visionaries driven by innovation and continuous improvement. Our charitable foundation also ensures that music education reaches underprivileged students around the globe. And with a genuine dedication to US manufacturing, environmentally sustainable practices, and a diverse family of passionate employees, what started in the Renaissance has become an ever-growing revolution.
Helicore Bio is developing long-acting therapies in obesity and cardiometabolic disease using our proprietary antibody-peptide conjugate platform.
We have developed proprietary libraries of GLP-1R agonist and amylin receptor agonist therapeutic peptides, optimized for relevant bias, selectivity, and potency characteristics. These peptides are designed for stability, driving intact conjugate durability, and conjugation to a variety of therapeutic antibodies via the Helicore conjugate platform.
Our conjugate pipeline is anchored with our proprietary GIP ligand binder antibody, which has demonstrated first-in-class safety, tolerability, and target engagement in our Phase 1 study.
Helicore is backed by world-class life science investors and led by a team with deep experience across drug discovery, development, and company building in metabolic disease.