Gknowmix Information

Gknowmix provides an integrated system for genetic testing service delivery involving healthcare practitioners, medical scientists, laboratories and the public. The objective is to identify gene-environment mismatches in an individual - that may be reflected by biochemical abnormalities or differential gene expression - and to use this information to facilitate the prevention of cumulative effects that may lead to disease development or progression. This approach includes the emerging disciplines of pharmacogenetics and nutrigenetics. It is based on the knowledge that a single genetic risk factor is not sufficient for the development or progression / recurrence of complex chronic disorders. Our unique test concept developed as part of an ethically approved translational research project combines the analysis of both high-penetrance genes (diagnostic, risk assessment) and low-penetrance genes (contributing factors, targets for treatment) in the context of the patient's medical history, clinical indicators, and lifestyle risk factors where appropriate. The genetic test results are provided in a comprehensive report - which not only focuses on disease diagnosis and treatment of symptoms - but also explains where possible how the expression of certain genes are influenced by modifiable environmental factors.