Computational Toxicology Services LLC Information

Computational Toxicology Services LLC specializes in supplying computer based quantitative structure-activity (QSAR) predictive toxicology screening of pharmaceuticals and the qualification of impurities in drug products. Computational toxicology is also used for the screening of indirect food additives. Computational Toxicology Services offers a cost effective solution for clients with toxicology screening needs that do not justify the investment in QSAR software licenses, database modules and trained staff necessary for computational toxicology screening of test substances. Computational toxicology can efficiently identify, prioritize and eliminate compounds with unacceptable safety profiles early in the product development process. A wide range of toxicology endpoints including mutagenicity, genotoxicity and carcinogenicity are available for the following software that are used extensively by industry and regulatory agencies:Derek-Nexus ( www.lhasalimited.org)Sarah-Nexus ( www.lhasalimited.org)Leadscope Model Applier (www.leadscope.com)Leadscope Expert Alert System (www.leadscope.com)Toxtree (http://ihcp.jrc.ec.europa.eu/our_labs/predictive_toxicology/qsar_tools/toxtree)