Centre for Infection and Immunity of Lille (CIIL) Information

Microbial and parasitic infections, as well as inflammatory diseases are today still the causes of high rates of morbidity and mortality world-wide.The understanding of infection and immunity, including non-infectious immune-dysregulation, obviously requires a multidisciplinary and integrated approach. The objectives of the CIIL lie precisely within this context. The CIIL is part of the Pasteur Institute of Lille and is composed of 11 research teams and 1 service facility on Transcriptomics and Genomics, organized in 3 major research areas: (i) Biology of the Pathogen, (ii) Strategies of Infection, and (iii) Host Response and Inflammatory Processes. It gathers complementary expertise, covering a wide range of disciplines from epidemiology, over molecular and cellular virology, bacteriology and parasitology, to the immunological basis of infectious and non-infectious diseases and translation into clinical applications. The targeted diseases include hepatitis C, tuberculosis and malaria. However, other diseases of increasing public health concern are also addressed, including plague, whooping cough, schistosomiasis, toxoplasmosis, various other parasitic, fungal, respiratory and gastro-intestinal infections. Furthermore, deciphering the dialogue with the symbiotic microbiota might provide novel clues in our understanding of chronic inflammatory diseases, such as inflammatory bowel disease, asthma and chronic obstructive pulmonary disease.