ATUM Information

ATUM is an industry-leading provider of life science contract research services, spanning gene synthesis, protein expression, protein engineering and cell line development. Founded as DNA2.0 in 2003, we are a pioneer in the application of machine learning to synthetic biology and hold multiple patents covering several technologies, including our first-to-market Leap-In Transposase® platform. ATUM is headquartered in Newark, California and all of our work is performed on-site. Why do people choose ATUM? Cell Line Development: Leap-In is the gold standard for cell engineering, producing high-expressing cell lines for biologics manufacturing. To date (Oct 2026) Leap-in transposase has been used to generate cell lines for 67 INDs by our partners in four territories. This work spans monoclonal antibodies to complex fusion proteins, bispecific and multispecific biologics. We have developed multiple transposases to not just express the biologic but to engineer the cell line. Protein Engineering: we have built better biologics, from enzymes to complex antibodies, by using lab-in-the-loop strategies to design, build and test. This is not high throughput screening; this is a thoughtful, methodical, science-based approach to correlating protein sequence to function. We will get you to your improved proteins faster than shotgun approaches. Vector design: we design better vectors to boost expression and balance chain ratios for complex biologics. Gene Synthesis: our codon-optimization algorithms, the earliest and best in the business, underpin every advancement described above. Good genes express good proteins.