ARTIC Information

Modern drug candidates are increasingly difficult to assess with standard static in vitro models, such as Caco2. Poor solubility, low permeability and complex test conditions can result in less reliable data, reducing confidence in compound selection before costly downstream development. To improve the predictive value of these assays, cell models need to better recreate the physiological conditions that influence drug behaviour in the human body. We bring controlled flow into familiar well-plate workflows, enabling more human-relevant models without adding complexity to the experiment. Our first application, FlowGUT, focuses on intestinal permeability assays. FlowIMMUNE targets immuno-oncology and immune-cell assays, where researchers need more relevant models to study immune-cell interactions and treatment response.