APICES Information

APICES is a full-service European Contract Research Organization specializing in clinical trials and real-world evidence research. With offices in Spain and France (formerly Kappa Santé), coverage across all major EU-5 markets and beyond, we combine scientific excellence with operational agility to accelerate high-quality clinical development. Founded in 2009 by experienced professionals from the pharmaceutical and CRO industries, APICES provides comprehensive services across Phases 0–IV and post-authorization studies. Our 100+ experts deliver integrated solutions in regulatory affairs, project management, clinical operations, data management, biostatistics, medical writing, safety, and pharmacoepidemiology. We have successfully conducted more than 450 clinical projects, partnering with 5,000+ investigators and enrolling over 100,000 patients. Our teams are recognized for strong expertise in oncology and hematology, as well as in cardiometabolic diseases, immunology, respiratory diseases, vaccines, rare diseases, and public health. APICES combines the scientific rigor and reliability of large organizations with the responsiveness, flexibility, and personalized approach of a mid-sized CRO. We design efficient studies, anticipate challenges, and ensure regulatory compliance and data integrity at every step. By integrating advanced analytics, digital tools, and real-world data, we help our partners in Pharma, Biotech, and Medtech demonstrate clinical and real-world value, improving patient outcomes and driving smarter healthcare decisions.