CNBE Information

A CRO specialized in exploratory animal studies, a state-of-the art animal research facility Located in the greater Montréal (Laval) GAP® certified (Good Animal Practice) A CRO specialized in exploratory animal studies: Toxicity Pharmacokinetic Drug-efficacy studies (proof-of-concept) Animal housing available for your own studies 78 multifunctional animal housing rooms (130,000 sq. ft.) Animal biosafety level 2 and 3 suites and studies Fast turnaround and flexibility CCAC and AAALAC International Accrediations CNBE's experienced staff can work with you to design and execute cost-effective protocols for your exploratory or screening studies. Services EXPLORATORY TOXICITY Dose-range finding (MTD, NOAEL, NOEL) Lethal dose 50% (LD50) Acute and chronic toxicity Testing of chemicals - fixed dose procedure (OECD 420) Immunotoxicity Skin reaction/Draize scoring/biopsies Delayed-type hypersensitivity (DTH) Blood chemistry/hematology/histopathology PHARMACOKINETIC Multiple routes of administration (per os, IV, IP, SC, IM, ID, IT and Ive) Multiple animal species (including non-human primate) Sampling & microsampling (sang, sera, plasma, urine, organs) PROOF-OF-CONCEPT STUDIES (DRUG EFFICACY) Infectious diseases (BSL-2; bacteria, virus, toxin, etc. ) Infectious diseases (BSL-3; bacteria, virus, toxin, etc.) Allergy (skin infiltration) Dermatology Stem cell safety Inflammation Arthritis Autoimmune diseases Oncology (syngenic, transgenic, xenograft) Vaccine Vaccine device (intradermal) Polyclonal antibody production Hypertension Hypercholesterolemy Hypertriglyceridemia Nutrition evaluation Wound healing and More Contact our team of experts: www.http://www.cnbe.inrs.ca/en